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CRISPR Pioneer Goes Small to Transform Genetic Medicine with Epigenetic Engineering

Epic Bioa biotech company founded by CRISPR co-inventor Stanley Qi, Ph.D., launchedTuesday with $55 million in Series A capital. The California-based company aims to transform genetic medicine by developing a new class of drugs that target the epigenome to alter gene expression. To help achieve its ambitions, Epic has the exclusive license for CasMINI, the …

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This is how the $100 human genome will change medicine

Ultima CEO Gilad Almogy, Ph.D./Courtesy of Ultima Genomics The information stored within the confines of the human genome is some of the most important data we can use in disease diagnosis, prevention efforts and therapies. Despite the fact that the technology to perform whole genome sequencing (WGS) has been around for decades, financial barriers have …

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Two-thirds of FDA-approved drugs backed with genetic data by 2021

Sarah Silbiger/Getty Images One of the tenets of ‘personalized medicine’ is that medicines are tailored to individuals based on their personalized genetics. Last year, the U.S. Food and Drug Administration’s Center for Drug Evaluation and Research approved 50 drugs. A new study found that 33, or 66% of them, were supported with genomic data. In …

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Money on the Move: Precigen, Syros, Zhiyi and Agile Raise Capital

As investment in the global life sciences industry declines, companies are raising money through means other than VC financing — they get money by selling subsidiaries, closing private placements and public offerings. BioSpace sheds light on some of these recent transactions. Precigen Sells Trans Ova Genetics With $170 Million Price Tag Maryland based Precigen is …

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Follow-up data on larotrectinib from Bayer point to a potential curative impact

Kena Betancur/VIEWpress/Corbis via Getty Images It’s been a month since cancer drug developers presented their latest research at the American Society of Clinical Oncology (ASCO) annual meeting, and the highlights still reverberate across the industry. Updates on Bayer’s Vitrakvi (larotrectinib) were: presented over several sessions, including one on the efficacy and safety of the oral …

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dr.  Louise Modis, CSO, Mogrify

Mogrify and Astellas Announce Collaboration to Investigate In Vivo Regenerative Medicines to Address Sensorineural Hearing Loss

CAMBRIDGE, UK and TOKYO, July 5, 2022 /PRNewswire/ — Mogrify Limited (CEO: Darrin M. Disley, Ph.D., “Mogrify“), a biopharmaceutical company transforming patients’ lives through a new class of in vivo reprogramming therapies, and Astellas Pharma Inc. (TSE: 4503), (President and CEO: Kenji Yasukawa, Ph.D., “Astellas”), a leader in regenerative medicine, today announced that they have …

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NYU researchers create synthetic versions of Hox genes

A team of researchers from New York University (NYU) has successfully created synthetic versions of the Hox genes that control biological development in humans, according to an article published in Science† Many of the recent biotech advances build on genome editing tools to correct a genetic component of a patient’s condition. Esteban Mazzoni, study co-author …

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Global Roundup: Olink publishes updated genetic atlas of the plasma protein

based in Sweden Olink Holding AB published an article describing the early findings of proteomics research conducted by the UK Biobank Pharma Proteomics Project. The article, “Genetic Regulation of the Human Plasma Proteome in 54,306 UK Biobank Participants,” was published online at the bioRxiv preprint server. The UK Biobank is a biomedical database and research …

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A woman vaping.

Rising e-cigarette use could lead to increase in tobacco smoking, Australia’s largest medical body warns

Australia’s top body for medical research says there is limited evidence that vapes help people quit smoking and that e-cigarettes may instead lead to an increase in tobacco smoke. Most important points: Professor Anne Kelso warns vaping users that the products can cause a range of medical problems, including seizures and lung injuries There are …

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