cancer

mRNA

Bayer and Amgen Join $120 Million Funding for Startup to Expand Genetic Drug Delivery

ReCode Therapeutics was founded around new science that may enable the delivery of genetic drugs to various organs in the body, and the startup has encouraging data for its therapeutic candidates targeting the lungs. Now the biotech startup $120 million to show that it can deliver on the technology’s promise in other organs and cell …

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Drug repurposing identifies new mesothelioma treatment candidates

Antonio Giordano Luciano Muttic Marcella Barbarino Newswise — A group of researchers led by Antonio Giordano, MD, Ph.D., director and founder of the Sbarro Health Research Organization (SHRO), Temple University, in collaboration with Stefano Landi, Ph.D.,. The chair of genetics at the University of Pisa, Italy, has identified potential new drug candidates for the treatment …

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Melanoma isn’t just caused by environmental factors like sun exposure, says new research – CBS Philly

PHILADELPHIA (CBS) — New research says melanoma, the most serious form of skin cancer, is not only caused by environmental factors such as sun exposure, but family history may also play a role. The number of melanomas is increasing rapidly, doubling in the past 30 years. It is more common in men in general, but …

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Another caveat in a red flag mesothelioma clinical trial in lancet oncology

Newswise – There is a growing awareness that clinical trial design can be misleading and provide evidence that ultimately does not benefit patients in the clinical setting. This discrepancy includes clinical trials testing the efficacy of new cancer treatments. A recent analysis shows that in the US, despite increased spending on cancer drugs in recent …

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Researchers discover a molecular switch that promotes the metastasis of pancreatic cancer

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA). PDA affects more than 90% of pancreatic cancer patients and has a mean 5-year survival rate of less than …

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Molecular tumor profiling in pediatric cancer patients has a significant impact on clinical care

Results from a molecular tumor profiling study in young patients revealed a high degree of genetic alterations potentially impacting clinical care, including clarifying diagnoses and treatment with matched, accurate cancer drugs. Report in naturopathyResearchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center said that molecular profiling of solid tumors found clinically significant genetic variations …

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Cancer risks are passed down from generation to generation for some families. But there are high hopes for precision medicine

Michelle Brady remembers how much her daughter Addie loved life. Most important points: Addie Brady was diagnosed with cancer at the age of 9 and 14 Genetic testing revealed she had an inherited mutation in the TP53 gene, known as the ‘guardian of the genome’ Researchers have high hopes for what precision medicine can do …

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New molecular information could help develop more effective treatments for melanoma

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer. In this new report, researchers from Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) identify and …

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Novartis Selects Precision Bio to Bring In Vivo Gene Editing Drugs for Blood Disorders

Genetic drugs in development for blood disorders include various therapies made by taking a patient’s cells and processing them outside the body. Novartis is one of the companies testing this approach, but also sees benefits in treating these diseases with therapies that work in the patient. The pharmaceutical giant is turning to Precision BioSciences’ technology …

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