gene expression

NUS researchers discover a new way to interpret unresolved Mendelian diseases

The development of an embryo is a well-orchestrated series of processes that ensure the correct formation and positioning of vital organs of the growing organism. At the molecular level, these processes are precisely controlled by switching certain factors such as genes or proteins on or off. Any errors in these processes can lead to physical …

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Researchers model a complex childhood disease on a chip

Millions of children in low- and middle-income countries suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the gut that is the second leading cause of death in children under the age of five. EED is a devastating condition associated with malnutrition, stunted growth and poor cognitive development, with a lasting impact on …

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