Gene

NUS researchers discover a new way to interpret unresolved Mendelian diseases

The development of an embryo is a well-orchestrated series of processes that ensure the correct formation and positioning of vital organs of the growing organism. At the molecular level, these processes are precisely controlled by switching certain factors such as genes or proteins on or off. Any errors in these processes can lead to physical …

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A computer rendering of neuronal inclusions in Huntington’s disease

Clinical challenges: NfL as an emerging biomarker in Huntington’s disease

Neurofilament light chain (NfL) shows promise as a biomarker for disease progression and prognosis in Huntington’s disease (HD), although clinical utility still lies ahead. Having better biomarkers is important, “even in a disease like HD that we know is monogenic, we know the causal mutation in the Huntington’s gene, and we can do predictive genetic …

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Study: Identification of critical genes and molecular pathways in COVID-19 myocarditis and constructing gene regulatory networks by bioinformatic analysis. Image Credit: Lightspring/Shutterstock

Study identifies crucial genes and biological pathways linked to COVID-19 myocarditis

Scientists from China recently deciphered the genetic network and biological mechanisms associated with the myocarditis of the 2019 coronavirus disease (COVID-19) using bioinformatic methods. They published their findings in the journal PLOS ONE† Study: Identification of critical genes and molecular pathways in COVID-19 myocarditis and the construction of gene regulatory networks by bioinformatic analysis† Image …

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Study: Identification of critical genes and molecular pathways in COVID-19 myocarditis and constructing gene regulatory networks by bioinformatic analysis. Image Credit: Lightspring/Shutterstock

Study identifies crucial genes and biological pathways linked to COVID-19 myocarditis

Scientists from China recently deciphered the genetic network and biological mechanisms associated with the myocarditis of the 2019 coronavirus disease (COVID-19) using bioinformatic methods. They published their findings in the journal PLOS ONE† Study: Identification of critical genes and molecular pathways in COVID-19 myocarditis and the construction of gene regulatory networks by bioinformatic analysis† Image …

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EXCLUSIVE Animal smugglers crawl back as pandemic restrictions ease – UN report

A pangolin walks during a press conference after Thai customs seized live pangolins, in Bangkok, Thailand Aug. 31, 2017. REUTERS/Prapan Chankaew/File Photo Register now for FREE unlimited access to Reuters.com Register SINGAPORE, Sept. 21 (Reuters) – Following a drastic cut in wildlife trade during the pandemic, authorities in Southeast Asia must act quickly to prevent …

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Molecular tumor profiling in pediatric cancer patients has a significant impact on clinical care

Results from a molecular tumor profiling study in young patients revealed a high degree of genetic alterations potentially impacting clinical care, including clarifying diagnoses and treatment with matched, accurate cancer drugs. Report in naturopathyResearchers at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center said that molecular profiling of solid tumors found clinically significant genetic variations …

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New molecular information could help develop more effective treatments for melanoma

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer. In this new report, researchers from Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) identify and …

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Researchers model a complex childhood disease on a chip

Millions of children in low- and middle-income countries suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the gut that is the second leading cause of death in children under the age of five. EED is a devastating condition associated with malnutrition, stunted growth and poor cognitive development, with a lasting impact on …

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